Remedial Properties

The natural solution for good health, a clear complexion, more energy and a long life. East Park Research's patented olive leaf extract products are natural, and our skin care products contain no Benzoyl Peroxide.

THERAPEUTIC COMPONENTS & THEIR BIOLOGICAL FUNCTIONS

Components and Biological Functions of Olive Leaves

1.	Carbohydrates — Manitol is present in therapeutically significant levels in the leaf and acts as a blood pressure and glucose modulator.
2.	Amino Acids & Enzymes
	a.	Amino Acids — Building Blocks of Proteins and Enzymes.
		Choline — Building block of lecithin and acetylcholine. Therefore important in fat transport and regulation of cholesterol and other lipids. Also critical to proper neurotransmission.
	b.	Enzymes
		Peroxidases — Agents responsible for oxidative degradation and biosynthesis of organic compounds. This applies to all olive leaf secondary metabolites.
		Esterases — Agent for breakdown of Oleuropein to its bioactive derivatives.
3.	Photosynthetic Pigments — These pigments (Chlorophylls and Carotinoids) help convert photo energy into chemical energy. They are also antioxidants via electron capture.
4.	Phenolic Acid Biological Activity
		Antioxidant (all but Tyrosol)
		Antimicrobial (all but Tyrosol)
		Anti-coagulant (Hydroxytyrosol)
		Anti-inflammatory (Hydroxytyrosol, Caffeic Acid, Eluthroside B, Chlorogenic Acid)

5.	Lignan Biological Activity
		Antioxidant
		Verbascoside, Elenoside
		Cytotoxicity (Anticancer)
		Elenoside is cytotoxic against leukemia, small cell lung cancer, breast, colon, and prostate cancers, at a concentration of 10^-5 to 10^-4 M.
6.	Flavanoid Biological Activity
		Antioxidant (all)
		Anti-inflammatory (Apigenin & Glycosides)
		Anti-allergenic (Apigenin, Luteolin)
		Vasodilator (All, especially flavanoids)
		Cytotoxic (Flavones)
		Smooth Muscle Relaxer (Flavones)
		Inhibits Clotting and Thrombosis (Chryseriol)
7.	Other Flavone Glycosides
		Apigenin-4-O-shamnoside 0.0015%
		Apigenin-7di-O-β-glucoside
		Apigenin-7-rutinoside
		Chryseriol-7-O-β-glucoside 0.00166%
		Luteolin-4’-O-β-D-glucoside 0.0001%
		Luteolin-7-O-β-D-glucoside
		Luteolin-7-O-β-D-rutinoside
		Luteolin-tetraglucoside
			Quercitin is the Aglycone of Rutin
			Olivin is an anticancer candidate with cytotoxic activity against hepatic tumors in vitro and in vivo in laboratory rats.
8.	Tannins — Tannins are antioxidants, metal chelaters, and protein precipitants. They are beneficial and non-deleterious to nutrition and health.
9.	Secoiridoids — Oleuropein & Related Compounds
		Secoiridoids are responsible for a significant part of the activity of Olive leaf extract. The derivatives of Oleuropein and Ligstroside are primarily responsible for the observed antimicrobial activity. Oleuropein and Ligstroside do not appear to possess any of this activity themselves. Oleacein, Oleuropein Aglycone, Oleuroside (an isomer of Oleuropein), various oleosides, and of course elolenic acid collectively possess the antimicrobial activity attributed to oleuropein.
10.	Saponins & Sterols
		Anticholesterolemic (Sterols)
			Antibiotic
			Antifungal
		Smooth Muscle Relaxant (Erythrodiol)
		Glucose Uptake Inhibitor (Maslinic Acid)
		Glucose modulator (Maslinic Acid)
11.	Alkaloids — Quinine Type Alkaloids are present and function as antimicrobials, particularly as antifungals and antiparasitics. They also are antifebrile. These are the original antimalarial drugs. Cinchonine and Cinchoninine alkaloids and sterioisomers.